CRE-Mediated Gene Transcription in Neocortical Neuronal Plasticity during the Developmental Critical Period
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منابع مشابه
CRE-Mediated Gene Transcription in Neocortical Neuronal Plasticity during the Developmental Critical Period
Neuronal activity-dependent processes are believed to mediate the formation of synaptic connections during neocortical development, but the underlying intracellular mechanisms are not known. In the visual system, altering the pattern of visually driven neuronal activity by monocular deprivation induces cortical synaptic rearrangement during a postnatal developmental window, the critical period....
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Neuronal plasticity in the brain is greatly enhanced during critical periods early in life and was long thought to be rather limited thereafter. Studies in primary sensory areas of the neocortex have revealed a substantial degree of plasticity in the mature brain, too. Often, plasticity in the adult neocortex lies dormant but can be reactivated by modifications of sensory input or sensory-motor...
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Critical Role of Histone Turnover in Neuronal Transcription and Plasticity
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ژورنال
عنوان ژورنال: Neuron
سال: 1999
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)80679-0